Zopiclone (Imovane) is indicated for the short-term therapy and symptomatic aid of insomnia characterised by difficulty in falling asleep, frequent nocturnal awakenings and/or early morning awakenings.
Treatment with zopiclone should often not exceed 7-10 consecutive days. Use for greater than 2-3 consecutive weeks requires full re-evaluation of the patient. Prescriptions for zopiclone must be written for short-term use (7-10 days) and it shouldn’t be prescribed in portions exceeding a 1-month supply.
The use of hypnotics must be restricted for insomnia where disturbed sleep results in impaired daytime functioning.
Imovane ought to solely be taken when you are able to get a full night’s sleep (7 to eight hours) earlier than you should be lively again.
The standard adult dose of zopiclone is one tablet simply before you go to mattress.
This treatment must be taken in a single consumption and never readministered during the identical night time.
If you may be over 65 years of age the dose is half a pill taken simply earlier than you go to mattress.
If you have a liver or kidney problem, the usual recommended dose is half a tablet taken just earlier than you go to bed.
Overdosage:
Overdose by zopiclone pills is usually manifested by various levels of central nervous system melancholy ranging from drowsiness to coma based on the quantity ingested. In gentle instances, signs embody drowsiness, confusion, and lethargy; in additional severe cases, symptoms may include ataxia, hypotonia, hypotension, methaemoglobinaemia, respiratory depression, and coma. Overdose shouldn’t be life threatening except combined with different CNS depressants, including alcohol. Other risk components, such because the presence of concomitant illness and the debilitated state of the patient, may contribute to the severity of symptoms and really hardly ever can result in deadly consequence.
In voluntary or accidental circumstances of zopiclone overdosage involving doses as much as 340 mg, the principal results reported were prolonged sleep, drowsiness, lethargy and ataxia.
Symptomatic and supportive therapy in sufficient scientific setting is beneficial, consideration should be paid to respiratory and cardiovascular functions. Gastric lavage or activated charcoal is only useful when carried out quickly after ingestion.
Hemodialysis is of no value due to the massive quantity of distribution of zopiclone. Flumazenil could additionally be a useful antidote; however, flumazenil administration could contribute to the appearance of neurological symptoms (agitation, anxiety, convulsionsand emotional lability). Intravenous fluids ought to be administered as wanted.
Свежие комментарии